#5871 PERITONEAL DIALYSIS INFECTIONS IN MALTA: AN OVERVIEW OF THIRTEEN YEARS

Abstract Background and Aims Peritoneal dialysis (PD)-related infections are still associated with an increased risk of morbidity mortality. We describe overview PD peritonitis catheter-related infection (CRI) rates in Malta over a period thirteen years. Method All patients undergoing from 2008 to 2020 were included. Data 2012 was retrospective (shown as mean), whilst data 2013 prospective. ISPD guidelines definitions followed. Results Study population sizes follows: 137 (2008-2012), 91, 80, 126, 117, 102, 103, 101, 101 respectively. 0.38, 0.31, 0.35, 0.46, 0.43, 0.57, 0.54, 0.39, 0.40, 0.37, 0.29 episodes/patient/year Gram-positive episodes predominated, the majority which Staphylococcal infections. Methicillin-resistant Staphylococcus aureus (MRSA) have overall decreased 0.03 episodes/patient 2008–2012 0.01 2020, no cases 2016, 2017 2019. Coagulase-negative (CNS) also 0.26 2017, 0.11 2018, 0.04 2019, 0.08 2020. With regards Gram-negative peritonitis, Pseudomonas declined 0.06 2018. No recorded 2019 The rate Escherichia coli-associated found Fungal varied 2013, being 2016 2017. CRI 0.39 0.91, 0.25, 0.50, 0.29, 0.22 incidence 49, 51, 52, 65, 58, 66, 48, 41% respectively, average 54%. CRIs mostly Staphylococcal, peaking 2014 at 0.38 episodes/patient, down 0.14 0.10 MRSA 0.15 improved 0.12 0.06, 0.09, 0.14, 0.03, 0.17, Conclusion Maltese cohort has been achieving target requirements. Both last There E. coli 2016,2017, 2018 fungal Overall predominantly Gram-negative, but not